There is a lack of a comprehensive immunohistochemical ihc analysis of canalicular adenoma canad, especially when combined with a description of the unique histologic features. Rarely, it manifests itself clinically and histologically as a multifocal lesion, a feature not generally seen with other intraoral salivary gland tumors. Bcac involving palatal minor salivary glands are exceedingly rare, and only 10 cases have been reported in the literature. These balls were attached or free floating, showing a metaplastic squamous appearance. Canalicular adenoma salivary gland, histology, pathologyvia pathpresenterfollow me on twitter. Given the usual small biopsies, ihc may be useful in distinguishing canad from other tumors in the differential diagnosis.
An 80yearold female presented with nine submucosal nodules of the upper labial mucosa and bilateral buccal mucosa. Analysis of the clinical relevance of histological. Differential diagnoses included a salivary adenoma, retention cyst of stensens duct or mucous retention cysts. The canalicular adenoma is an uncommon, benign salivary gland neoplasm that usually occurs in or near the upper lip of elderly patients. Canalicular adenoma cad is an uncommon benign tumor of minor salivary glands with predilection for the upper labial mucosa. As observed in several other sgts, a commonly encountered finding is the presence of prominent cystic morphology. Canalicular adenoma is a benign neoplasm of a salivary glands which originally was considered to be a variant of basal cell adenoma. Despite this predilection for the upper lip, there are reports of canalicular adenomas occurring in the lower lip. On this basis adenoma sebaceum pringle and senile sebaceous adenoma are generally no longer considered adenomas. The canalicular adenoma is an uncommon benign salivary tumor with distinct histological characteristics and a proclivity for the upper lip, followed by the buccal mucosa and palate and rarely the parotid gland. Along with pleomorphic adenoma demographics, we present the first nationwide study with long. Canalicular adenoma canad is an uncommon benign salivary gland neoplasm. Canalicular adenoma does not commonly occur in the palate. Canalicular adenoma ca is a benign tumor that develops in the accessory.
Despite its benign nature, some patients may present multiple nodules and also microscopic. Canalicular adenoma is a benign salivary gland neoplasm. Ca has a significant predilection for occurrence in the minor. For the immunohistochemical reactions by the polymeric biotin free technique. Canalicular adenoma type of benign salivary gland tumor occurs most often in minor salivary glands. A histologic study of 49 tumors revealed that they are often multifocal, may infiltrate their capsule, and are occasionally unencapsulated. Clinical, morphological and immunohistochemical findings in. A high proportion of canalicular adenomas occur in the upper lip, a predilection not evident in other salivary gland tumours 4. Salivary lab free download as powerpoint presentation. In the past, there was difficulty differentiating benign salivary gland tumors because the classification schemes failed to separate canalicular adenoma from other. Basal cell adenoma bca of the salivary glands is a rare tumour, recognised as an independent entity in the second edition of the salivary gland tumours classification of the world health organization who 1.
Histopathologic examination revealed multifocal circumscribed tumor islands with a tubular growth pattern within a loose hypocellular myxoid background. Oct 01, 2007 canalicular adenomas cas generally occur during the seventh decade and have a 2. It seems that canalicular adenoma is similar to basal cell adenoma of the parotid only in the formation of small cystic spaces that contain some amorphous cell debris. Background ca is an uncommon benign neoplasm that can develop in minor salivary gland duct tissues throughout the oral cavity. Histopathologic examination revealed multifocal circumscribed tumor islands with a tubular growth pattern within a loose hypocellular myxoid. If you want to participate andor join, please visit the project page, or ask questions on the project talk page. It occurs almost exclusively in the upper lips, next common site being the buccal mucosa. It is most common in the 7th decade of life but can occur from 4th to 9th decades of life.
The evidence that canalicular adenomas and basal cell adenomas are separate entities is presented in this article. The clinical features were studied in a series of previously unreported salivary gland tumors 5 canalicular adenomas and 8 basal cell adenomas and 99 examples derived from the literature 68 canalicular adenomas and 31 basal. Ca is an uncommon benign neoplasm that can develop in minor salivary gland duct tissues throughout the oral cavity. Bilateral canalicular adenoma of the parotid gland. Aug 21, 2014 canalicular adenoma canad is an uncommon benign salivary gland neoplasm. Dec 01, 2014 objectives to report a case of canalicular adenoma ca and discuss the use of immunohistochemistry to better address the diagnosis given some unusual characteristics in this patient. Oct 01, 2017 canalicular adenoma is an uncommon salivary neoplasm affecting almost exclusively the minor salivary glands, and representing % of all salivary tumors nelson and jacoway, 1973, batsakis, 1991, furuse et al. Monomorphic adenoma of the minor salivary glands the journal.
Whether or not true adenoma of sebaceous glands exists is still an unsettled question. Other locations arebuccal mucosa, the palate and the parotid gland. Canalicular adenomas represent 1% of all salivary gland neoplasms and 4% of minor salivary gland neoplasms. Canalicular adenoma affects primarily adults and presents at a mean age of approximately 60 years. A56 year old female patient with asymptomatic intramandibular canalicular adenoma was presented. Salivary gland tumors free download as powerpoint presentation. Sep 18, 2015 pleomorphic adenoma is the most frequent salivary gland tumor and is known for its tendency to recur and for its ability to transform to carcinoma ex pleomorphic adenoma ca.
Their incidence peaks during the seventh decade of life. Canalicular adenoma is an uncommon benign neoplasm of the salivary glands. The most common site of occurrence is the upper lip. Canalicular adenoma ca is an uncommon benign salivary gland tumor that mostly occurs in the upper lip. Canalicular adenoma is a benign salivary gland tumor that was defined by world health organization classification in 1991. Canalicular adenoma salivary gland, histopathology youtube. Other locations include the buccal mucosa, the palate, and the parotid gland. At histology, it shares several features with other salivary tumors. Canalicular adenoma ca is a benign neoplasia of salivary glands, which although representing less than 1% of salivary gland tumours, is the second or third most common benign tumour of minor. Basal cell adenocarcinoma of the minor salivary glands. The term canalicular adenoma was first coined by mcfarland in 1942. Canalicular adenoma is rare benign tumor of minor salivary glands and it is rarely found in major salivary glands. Nov 17, 2019 canalicular adenoma is a benign, epithelial salivary gland neoplasm arranged in interconnecting cords of columnar cells.
Canalicular adenoma ca is a benign neoplasm that can manifest from minor salivary gland ductal tissue throughout the oral cavity and infrequently in the parotid gland. A rare presentation of canalicular adenoma of the parotid. Mar 02, 2021 canalicular adenoma is a benign neoplasm of a salivary glands which originally was considered to be a variant of basal cell adenoma. Canalicular adenoma is an uncommon salivary neoplasm affecting almost exclusively the minor salivary glands, and representing % of all salivary tumors nelson and jacoway, 1973, batsakis, 1991, furuse et al. In most cases 393534 of pleomorphic adenoma, a precise diagnosis was given. The authors report the fifth case and the first in the otorhinolaryngological literature of a canalicular adenoma of the parotid gland.
Canalicular adenoma wikimili, the free encyclopedia. Basal cell adenoma bca and canalicular adenoma ca are rare salivary gland tumors. Canalicular adenoma johns hopkins surgical pathology. These tumors have undergone taxonomic drift, with many terms used to describe these tumors over the years table. Files are available under licenses specified on their description page. Canalicular adenoma definition of canalicular adenoma by. The majority of cases involve the upper lip, presenting as single or multiple masses. Canalicular adenoma arising in the esophagus archives of.
Canalicular adenomas from five patients were examined by light and electron microscopy. Canalicular adenomas are uncommon, benign epithelial neoplasm of the salivary glands that. We carried out a survey of cases of cads among the all salivary gland tumors submitted to an oral pathology service over a 36year period, and performed a. Pleomorphic adenomas are the most common benign tumors of salivary glands and occur mainly in the parotid gland. Originally thought to be derived from terminal duct origin 1, 2, there has been controversy about origin and separation from other salivary gland neoplasms. Canalicular adenoma is a rare benign tumor arising almost exclusively within minor. Canalicular adenoma accounts for 1% of all salivary gland tumors. It is necessary to differentiate bcac from other basaloid cell tumors of the minor salivary glands such as canalicular adenoma, bca, adenoid cystic carcinoma, polymorphous lowgrade adenocarcinoma. Within oral cavity upper lip is the most common site for this tumor followed by buccal mucosa and sometimes it.
The canalicular adenoma is a benign tumor that has a significant predilection for the upper lip figure 10. Canalicular adenoma of the parotid gland the journal of. Canalicular adenoma cad is an uncommon benign salivary gland tumor. Canalicular adenomas are uncommon, benign epithelial neoplasm of the salivary glands that usually involve the. The term canalicular adenoma was first coined by mcfarland2 in 1942, and.
Congratulations to the scott gwinnell jazz orchestra, winner of our april pandemic music relief award. Article information, pdf download for basaloid monomorphic adenomas open. Accepted for publication 11 april 2005 introduction case reports canalicular adenoma is an uncommon, benign saliv case 1 ary gland tumour, which occurs. Pdf cytological features of intraoral tumour jacks. May 15, 2015 basal cell adenoma is a benign salivary gland tumor that also primarily occurs in the parotid gland. With the exception of the canalicular adenoma, the basaloid monomorphic. Pdf cytological features of intraoral tumour jacks jorge. Canalicular adenoma is a benign, epithelial salivary gland neoplasm arranged in interconnecting cords of columnar cells. Clinical and histological features of multifocal canalicular. Nly a few cases of canalicular adenoma have been previously reported.
We describe to our knowledge the first case of a canalicular adenoma of the. Canalicular adenoma cad is an uncommon benign salivary gland tumor, usually located in the upper lip. This article is within the scope of wikiproject medicine, which recommends that medicinerelated articles follow the manual of style for medicinerelated articles and that biomedical information in any article use highquality medical sources. This is a very rare benign neoplasm, that makes up about 1% of all salivary gland tumors, or about 4% of all benign salivary gland tumors. Canalicular adenomas are rare benign tumours of the salivary glands, almost exclusively found in the upper lips and have a multifocal tendency. Synchronous multifocal canalicular adenomas springerlink. Canalicular adenoma a case report of a rare benign tumor of. All structured data from the file and property namespaces is available under the creative commons cc0 license. Canalicular adenoma a case report of a rare benign tumor. Fine needle aspiration introduction canalicular adenoma ca is an uncommon, benign salivary gland tumor that was described by the world health organization classification in 1991 1.
Canalicular adenoma constitutes 4% of the minor salivary gland neoplasms and only 1% all salivary gland tumors. The upper lip is the site most often involved for ca, whereas bca. Pdf multifocal canalicular adenoma of the upper lip. Mar 01, 2005 canalicular adenomas are benign neoplasms with a unique predilection for the upper lip 80% of cases. After pleomorphic adenoma and mucoepidermoid carcinoma, it is the third common salivary gland tumor. A rare presentation of canalicular adenoma of the parotid gland. Accepted for publication 11 april 2005 introduction case reports canalicular adenoma is an uncommon, benign saliv case 1. Wikiproject dentistry rated startclass, lowimportance this article is supported by wikiproject dentistry. Canalicular adenomas cas are uncommon benign salivary gland neoplasms of the oral cavity. Canalicular adenomas are a rare form of benign tumour that occur in salivary glands, occurring mainly in the upper lip and minor salivary glands of the buccal mucosa. Canalicular adenoma ca is a benign salivary gland tumor sgt almost exclusively affecting the minor salivary glands, predominantly of the upper lip, and exhibiting characteristic histopathologic features. They account for 1% of all salivary gland neoplasms.
Canalicular adenoma composed of columnar epithelial cells arranged in single or double layer forming branching. The canalicular adenoma is an uncommon, benign salivary gland tumor that most frequently occurs in the upper lip. Pleomorphic adenoma has a rather high risk for recurrence while recurrence occurs only occasionally in sialadenoma papilliferum, oncocytoma, canalicular adenoma, myoepithelioma and the membranous type of basal cell adenoma. It has a greater tendency to involve the minor salivary glands. Immunohistochemical profile of canalicular adenoma of the. The canalicular adenoma is an uncommon, benign salivary gland tumor that most frequently occurs. Basal cell adenocarcinoma bcac is a rare neoplasm accounting for only 2. The canalicular adenoma is an uncommon, benign salivary gland neoplasm that. Keywords canalicular adenoma 4 lip 4 buccal 4 palate 4. Canalicular adenoma is the second most common type of adenoma of the oral region and arises almost exclusively in the upper lip. Fine needle aspiration cytology of benign salivary gland tumors.
1427 1426 888 974 17 607 1206 1299 1590 1649 188 848 380 554 295 560 1295 106 111 865 53 778 1354 908 1580 45 1256 572 1309 852 613 1104 1452 919 1103 1257 932 78